Clocksclub

Lab: (314) 935-5214 Email: herzog@biology2.wustl.edu

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ClocksClub

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Clocksclub

Clocksclub is a journal club that discusses recent advances in the study of biological timing. Semi monthly meetings are coordinated by the labs of Erik Herzog (Biology), Russ Van Gelder (Ophthalmology), Paul Taghert ( Anatomy and Neurobiology), Lou Muglia (Pediatrics), Paul Gray ( Anatomy and Neurobiology) and Paul Shaw ( Anatomy and Neurobiology). To receive announcements on the Clocksclub mailing list, send your name and Email to Erik Herzog.

Summer Schedule

"Time Series Analysis Turorial" McDonnell 312 (Danforth Campus, Bldg #58 on this map http://www.biology.wustl.edu/faculty/herzog/campusmap.pdf)

Aug. 17, 1:00-2:30. Estimations of rhythmicity and period

MESA
FFT-NLLS
Chi-squared periodogram
Autocorreclation
Cross-over
RI, Power, Rel-amp, Op, signal-to-noise

Aug. 31, 2:30-4:00 Sampling, signal conditioning and plotting

methods to remove noise
knowing the limits of your data (rules of stationarity)
plots to emphasize period, waveform, and phase relationships

Sept. 7, 2:30-4:00. Estimations of phase and coherency

Raleigh plots and statistics
Cross-correlation

Past Tutorials

Entrainmentis the process by which an oscillator synchronizes to a periodic input, like how we sync to the daily light-dark cycle. This tutorial, aimed at students of biological timing who wish to explore the various models of how circadian pacemakers entrain to daily cues, starts with classic readings by Colin Pittendrigh. We will meet in the same place and time as Clocksclub.

Semiar

1 Phase response curves: pedictive value

2 Dawn to dusk and jet lag: Evidence for parametric vs. non-parametric entrainment

3 A clock for all seasons: Coupled (E&M) oscillators

4 Limit cycle oscillators

Additional helpful readings
Johnson CH, Elliot JA, Foster R. (2003) Entrainment of circadian programs. Chronobiol Int. 20:741-74.
Deersma DG, Daan S, Hut RA. (1999) Accuracy of circadian entrainment under fluctuating light conditions: contributions of phase and period responses. J. Biol Rhythms. 14:320-9.
Limit cycle oscillators: relating the PRC and oscillator amplitude Winfree Chapter 1 Winfree Chapter 5